Reducing inter-scanner variability of activation in a multicenter fMRI study: Role of smoothness equalization

• Published in: NeuroImage (Orlando, Fla.) Vol. 32; no. 4; pp. 1656 - 1668
• Main Authors: Friedman, Lee, Glover, Gary H., Krenz, Diana, Magnotta, Vince
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2006; Elsevier Limited
• Subjects: Adult; Brain research; Calibration; Data Interpretation, Statistical; Disease; Echo-Planar Imaging; Factor Analysis, Statistical; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging - instrumentation; Male; Phantoms, Imaging; Scanners; Schizophrenia; Studies
• ISSN: 1053-8119; 1095-9572
• DOI: 10.1016/j.neuroimage.2006.03.062

Scanner-to-scanner variability of activation in multicenter fMRI studies is often considered undesirable. The purpose of this investigation was to evaluate the effect of a new procedure, “smoothness equalization”, on reducing scanner differences in activation effect size as part of a multicenter fMR...