Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis

• Published in: Stem cell research & therapy Vol. 16; no. 1; pp. 409 - 19
• Main Authors: Hua, Zilin, Zhou, Nan, Zhou, Zijing, Fu, Zewei, Guo, Ruiyun, Akogo, Herman Yao, Yang, Jiayin, Yu, Meixuan, Jiang, Yujie, Lan, Siyi, Chang, Haixia, Ma, Jun, Cui, Huixian
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.07.2025; BioMed Central; BMC
• Subjects: Advertising executives; Alzheimer's disease; Analysis; Brain research; Cell death; Derivatives (Financial instruments); Health aspects; Intranasal administration; Medical research; Medicine, Experimental; Meta-analysis; Nervous system diseases; Neurons; Review; Stem cell derivative; Stem cells; Systematic review; Transplantation; Illinois; Systematic review; Intranasal administration; Alzheimer’s disease; Meta-analysis; Stem cell derivative

Background Alzheimer's disease (AD) is a neurodegenerative disorder with increasing prevalence and limited efficacy of current therapies. Stem cell-derived therapies have attracted attention for their potential neurodegenerative and reparative effects. Intranasal administration provides a non-i...