use of transcriptional profiles to predict adult mosquito age under field conditions

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 103; no. 48; pp. 18060 - 18065
• Main Authors: Cook, P.E, Hugo, L.E, Iturbe-Ormaetxe, I, Williams, C.R, Chenoweth, S.F, Ritchie, S.A, Ryan, P.A, Kay, B.H, Blows, M.W, O'Neill, S.L
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 28.11.2006; National Acad Sciences
• Subjects: adult insects; Aedes aegypti; Age; Age structure; Aging - genetics; animal age; Animals; Biological Sciences; Calibration; Culicidae - genetics; Datasets; Disease transmission; Gene expression; Gene Expression Profiling; Genes; Hydrocarbons; insect cuticle; Linear regression; messenger RNA; Modeling; Mosquitoes; Mosquitos; Polymerase chain reaction; prediction; RNA; transcription (genetics); Transcription, Genetic - genetics; transcriptional profiling; United States > US

Age is a critical determinant of an adult female mosquito's ability to transmit a range of human pathogens. Despite its central importance, relatively few methods exist with which to accurately determine chronological age of field-caught mosquitoes. This fact is a major constraint on our abilit...