Co-targeting RNA Polymerases IV and V Promotes Efficient De Novo DNA Methylation in Arabidopsis

• Published in: Cell Vol. 176; no. 5; pp. 1068 - 1082.e19
• Main Authors: Gallego-Bartolomé, Javier, Liu, Wanlu, Kuo, Peggy Hsuanyu, Feng, Suhua, Ghoshal, Basudev, Gardiner, Jason, Zhao, Jenny Miao-Chi, Park, Soo Young, Chory, Joanne, Jacobsen, Steven E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 21.02.2019; Cell Press
• Subjects: Arabidopsis; Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; biogenesis; cytosine; Cytosine - metabolism; DNA - metabolism; DNA methylation; DNA Methylation - genetics; DNA Methylation - physiology; DNA-directed RNA polymerase; DNA-Directed RNA Polymerases - genetics; DNA-Directed RNA Polymerases - metabolism; epigenetics; gene expression; Gene Expression Regulation, Plant - genetics; genes; mutants; proteins; RNA Polymerase II - metabolism; RNA, Plant - genetics; RNA, Small Interfering - metabolism; small interfering RNA; zinc finger motif

The RNA-directed DNA methylation (RdDM) pathway in plants controls gene expression via cytosine DNA methylation. The ability to manipulate RdDM would shed light on the mechanisms and applications of DNA methylation to control gene expression. Here, we identified diverse RdDM proteins that are capabl...