Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration - Liu, Lucy; Zhang, Ke; Sandoval, Hector; Yamamoto, Shinya; Jaiswal, Manish; Sanz, Elisenda; Li, Zhihong; Hui, Jessica; Graham, Brett H.; Quintana, Albert; Bellen, Hugo J. (Cell, 2015)
Keywords: Animals; binding proteins; carboxylic ester hydrolases; droplets; Drosophila; Electron Transport Complex I - genetics; Electron Transport Complex I - metabolism; Lipid Droplets - metabolism; lipid peroxidation; lipids; MAP Kinase Kinase 4 - metabolism; Mice; Mice, Knockout; mitochondria; Mitochondria - metabolism; mitogen-activated protein kinase; mutants; neurodegenerative diseases; Neurodegenerative Diseases - metabolism; Neurodegenerative Diseases - pathology; Neuroglia - metabolism; Neuroglia - pathology; neurons; Neurons - pathology; reactive oxygen species; Reactive Oxygen Species - metabolism; Sterol Regulatory Element Binding Proteins - metabolism