Reduced sCD36 following weight loss corresponds to improved insulin sensitivity, dyslipidemia and liver fat in obese children

• Published in: European journal of clinical nutrition Vol. 70; no. 9; pp. 1073 - 1077
• Main Authors: Knøsgaard, L, Kazankov, K, Birkebæk, N H, Holland-Fischer, P, Lange, A, Solvig, J, Hørlyck, A, Kristensen, K, Rittig, S, Vilstrup, H, Grønbæk, H, Handberg, A
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2016; Nature Publishing Group
• Subjects: 692/163/2743/2099; 692/163/2743/393; 692/499; 692/53; Accumulation; Adipose Tissue - metabolism; Adolescent; Biomarkers - blood; Biomarkers - metabolism; Blood Glucose - metabolism; Body fat; Body Mass Index; Body weight loss; Care and treatment; CD36 antigen; CD36 Antigens - blood; Cellular proteins; Child; Childhood obesity; Children; Children & youth; Cholesterol; Cholesterol - blood; Clinical Nutrition; Development and progression; Dyslipidemia; Dyslipidemias - blood; Epidemiology; Fatty Liver - blood; Female; Genetic aspects; Health aspects; Health risks; Homeostasis; Humans; Inflammation - blood; Insulin; Insulin - blood; Insulin Resistance; Internal Medicine; Lipids; Lipids - blood; Liver; Liver - metabolism; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic disorders; Metabolic Syndrome - blood; Metabolism; Obesity; original-article; Pediatric Obesity - blood; Pediatric Obesity - complications; Pediatric Obesity - therapy; Plasma; Public Health; Triglycerides; Triglycerides - blood; Weight control; Weight loss; Weight Loss - physiology; Weight reduction

Background/Objectives: Childhood obesity is a major health problem with serious long-term metabolic consequences. CD36 is important for the development of obesity-related complications among adults. We aimed to investigate circulating sCD36 during weight loss in childhood obesity and its association...