Multi‐Beat Right Ventricular‐Arterial Coupling Predicts Clinical Worsening in Pulmonary Arterial Hypertension

• Published in: Journal of the American Heart Association Vol. 9; no. 10; p. e016031
• Main Authors: Hsu, Steven, Simpson, Catherine E., Houston, Brian A., Wand, Alison, Sato, Takahiro, Kolb, Todd M., Mathai, Stephen C., Kass, David A., Hassoun, Paul M., Damico, Rachel L., Tedford, Ryan J.
• Format: Journal Article
• Language: English
• Published: England Ovid Technologies (Wolters Kluwer Health) 18.05.2020; John Wiley and Sons Inc; Wiley
• Subjects: Adult; Aged; Arterial Pressure; Cardiac Catheterization; Diseases of the circulatory (Cardiovascular) system; Female; Heart Rate; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Original Research; outcome; Predictive Value of Tests; pressure‐volume relationship; Prognosis; Prospective Studies; Pulmonary Arterial Hypertension; Pulmonary Arterial Hypertension - diagnosis; Pulmonary Arterial Hypertension - physiopathology; Pulmonary Artery; Pulmonary Artery - physiopathology; pulmonary hypertension; RC666-701; Reproducibility of Results; right ventricular dysfunction; Ventricular Dysfunction, Right; Ventricular Dysfunction, Right - diagnosis; Ventricular Dysfunction, Right - physiopathology; Ventricular Function, Right; pressure‐volume relationship; right ventricular dysfunction; pulmonary hypertension; outcome

Background Although right ventricular (RV) to pulmonary arterial (RV-PA) coupling is considered the gold standard in assessing RV dysfunction, its ability to predict clinically significant outcomes is poorly understood. We assessed the ability of RV-PA coupling, determined by the ratio of multi-beat...