Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities - Li, Xiaofei; Wang, Hui; Yu, Xiang; Saha, Gundappa; Kalafati, Lydia; Ioannidis, Charalampos; Mitroulis, Ioannis; Netea, Mihai G.; Chavakis, Triantafyllos; Hajishengallis, George (Cell, 2022)
Keywords: Animals; Arthritis; bone marrow; bone marrow transplantation; comorbidities; disease severity; epigenetic rewiring; epigenetics; hematopoietic stem and progenitor cells; Hematopoietic Stem Cells; Immunity, Innate; inflammation; innate immunity; interleukin-1; Mice; Myelopoiesis; Periodontitis; phenotype; progeny; trained immunity; comorbidities; arthritis; inflammation; myelopoiesis; periodontitis; hematopoietic stem and progenitor cells; epigenetic rewiring; trained immunity; bone marrow transplantation