Sensitivity to implant materials in patients with total knee arthroplasties

• Published in: Biomaterials Vol. 29; no. 10; pp. 1494 - 1500
• Main Authors: Granchi, Donatella, Cenni, Elisabetta, Tigani, Domenico, Trisolino, Giovanni, Baldini, Nicola, Giunti, Armando
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.04.2008
• Subjects: Adult; Advanced Basic Science; Aged; Aged, 80 and over; Alloys - adverse effects; Alloys - chemistry; Arthroplasty, Replacement, Knee - adverse effects; Arthroplasty, Replacement, Knee - methods; Cobalt - adverse effects; Cobalt - chemistry; Cobalt alloy; Dentistry; Female; Humans; Hypersensitivity; Knee Prosthesis - adverse effects; Knee replacement; Male; Materials Testing - methods; Middle Aged; Patch Tests - methods; Prospective Studies; Titanium - adverse effects; Titanium - chemistry; Titanium alloy; Titanium alloy; Knee replacement; Hypersensitivity; Cobalt alloy

Materials used for total knee arthroplasty (TKA), may elicit an immune response whose role in the outcome of the arthroplasty is still unclear. The aim of this study was to evaluate the frequency of sensitization in patients who had undergone TKA, and the clinical impact of this event on the outcome...