The assessment of hemispheric lateralization in functional MRI—Robustness and reproducibility

• Published in: NeuroImage (Orlando, Fla.) Vol. 33; no. 1; pp. 204 - 217
• Main Authors: Jansen, A., Menke, R., Sommer, J., Förster, A.F., Bruchmann, S., Hempleman, J., Weber, B., Knecht, S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.10.2006; Elsevier Limited
• Subjects: Adult; Algorithms; Attention - physiology; Attention deficit hyperactivity disorder; Brain; Brain - anatomy & histology; Brain - physiology; Brain research; Decision Making - physiology; Dominance, Cerebral - physiology; Female; fMRI; Functional Laterality - physiology; Humans; Image Processing, Computer-Assisted; Language; Lateralization; Magnetic Resonance Imaging; Male; NMR; Nuclear magnetic resonance; Psycholinguistics; Reliability; Reproducibility; Reproducibility of Results; Space Perception - physiology; Studies; SDT; WGT; LT; rPF; ROI; Lateralization; CTA; fMRI; WH; Reproducibility; PNT; TP; Reliability; LI

Various methods have been proposed to calculate a lateralization index (LI) on the basis of functional magnetic resonance imaging (fMRI) data. Most of them are either based on the extent of the activated brain region (i.e., the number of “active” voxels) or the magnitude of the fMRI signal change. T...