Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections

• Published in: Computational and structural biotechnology journal Vol. 19; pp. 4092 - 4100
• Main Authors: Mercatelli, Daniele, Pedace, Elisabetta, Veltri, Pierangelo, Giorgi, Federico M., Guzzi, Pietro Hiram
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2021; Research Network of Computational and Structural Biotechnology; Elsevier
• Subjects: Ageing genes; biotechnology; COVID-19; COVID-19 infection; data collection; Data science; death; elderly; gender; gene expression; humans; Interactomes; lungs; people; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; viruses; COVID-19; Data science; SARS-CoV-2; Ageing genes; Interactomes

[Display omitted] Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related to the age of patients. While ageing has been extensivel...