Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming - Schiebinger, Geoffrey; Shu, Jian; Tabaka, Marcin; Cleary, Brian; Subramanian, Vidya; Solomon, Aryeh; Gould, Joshua; Liu, Siyan; Lin, Stacie; Berube, Peter; Lee, Lia; Chen, Jenny; et al. (Cell, 2019)
Keywords: ancestors; Animals; Cell Differentiation - genetics; Cells, Cultured; Cellular Reprogramming - genetics; cytokines; descendants; development; Embryonic Stem Cells - metabolism; Fibroblasts - metabolism; Gene Expression; Gene Expression Profiling - methods; Gene Expression Regulation, Developmental - genetics; Induced Pluripotent Stem Cells - metabolism; iPSCs; Mice; optimal-transport; paracrine interactions; regulation; reprogramming; scRNA-seq; sequence analysis; Sequence Analysis, RNA - methods; Single-Cell Analysis - methods; trajectories; transcription factors; Transcription Factors - metabolism; reprogramming; iPSCs; optimal-transport; scRNA-seq; development; paracrine interactions; regulation; trajectories; ancestors; descendants