Making the Final Cut — Mechanisms Mediating the Abscission Step of Cytokinesis

• Published in: TheScientificWorld Vol. 10; pp. 1424 - 1434
• Main Authors: Schiel, John A., Prekeris, Rytis
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.01.2010; TheScientificWorldJOURNAL; Wiley
• Subjects: Actins - metabolism; Animals; Cell Membrane - metabolism; Cell membranes; Cytokinesis; Cytokinesis - physiology; Cytoskeleton - metabolism; Endosomes - metabolism; Health aspects; Humans; Microtubules - physiology; Mini-Review; Models, Biological; Myosin; Physiological aspects; Spindle Apparatus - physiology; United States

Cytokinesis is the final stage of mitotic cell division that results in a physical separation of two daughter cells. Cytokinesis begins in the early stages of anaphase after the positioning of the cleavage plane and after the chromosomes segregate. This involves the recruitment and assembly of an ac...