Diabetes mellitus, vitamin D & osteoporosis: Insights
The worsening of glycaemic control in diabetic patients during winter was also attributed to lowering of vitamin D levels during those months. [...]recently, these notions were driving clinicians to consider routine supplementation of vitamin D to patients with diabetes mellitus. [...]Wallace et al[...
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Published in | Indian journal of medical research (New Delhi, India : 1994) Vol. 150; no. 5; pp. 425 - 428 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
India
Wolters Kluwer India Pvt. Ltd
01.11.2019
Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow |
Subjects | |
Online Access | Get full text |
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Summary: | The worsening of glycaemic control in diabetic patients during winter was also attributed to lowering of vitamin D levels during those months. [...]recently, these notions were driving clinicians to consider routine supplementation of vitamin D to patients with diabetes mellitus. [...]Wallace et al[26], showed absence of any effect of vitamin D supplementation on insulin resistance, beta cell dysfunction and glycaemic control in diabetic patients. [...]it seems vitamin D has no major-independent role in glycaemic control among patients with diabetes. Reciprocally, the action of insulin on osteoblastic receptors activates osteoclastic activity and increased undercarboxylated OC, resulting in a feed forward loop[30]. [...]the area of bone health in DM requires in-depth research in multiple areas such as alteration in bone quality, methods to investigate perturbed bone microarchitecture, diagnostic criteria for osteoporosis and choice of anti-osteoporotic medicines for best bone health. |
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Bibliography: | SourceType-Other Sources-1 content type line 63 ObjectType-Editorial-2 ObjectType-Commentary-1 This editorial is published on the occasion of the World Diabetes Day - November 14, 2019 |
ISSN: | 0971-5916 |
DOI: | 10.4103/ijmr.IJMR_1920_19 |