Correlation of Obesity and Osteoporosis: Effect of Fat Mass on the Determination of Osteoporosis

• Published in: Journal of bone and mineral research Vol. 23; no. 1; pp. 17 - 29
• Main Authors: Zhao, Lan‐Juan, Jiang, Hui, Papasian, Christopher J, Maulik, Dev, Drees, Betty, Hamilton, James, Deng, Hong‐Wen
• Format: Journal Article
• Language: English
• Published: Washington, DC John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR) 01.01.2008; American Society for Bone and Mineral Research; Amer Soc Bone & Mineral Res
• Subjects: 11-beta-Hydroxysteroid Dehydrogenases - physiology; Adipocytes - cytology; Adiponectin - physiology; Adipose Tissue - metabolism; Amyloid - physiology; Aromatase - physiology; Biological and medical sciences; Bone Density; Cell Differentiation; correlation; fat mass; Female; Fundamental and applied biological sciences. Psychology; Humans; Insulin - physiology; Insulin-Like Growth Factor II - physiology; Interleukin-6 - physiology; Islet Amyloid Polypeptide; Leptin - physiology; Male; obesity; Obesity - complications; Obesity - physiopathology; Osteoblasts - cytology; osteoporosis; Osteoporosis - complications; Osteoporosis - physiopathology; Peptide Fragments - physiology; PPAR gamma - physiology; Resistin - physiology; Review; Skeleton and joints; Transforming Growth Factor beta - physiology; Vertebrates: osteoarticular system, musculoskeletal system; Wnt Proteins - physiology; Osteoarticular system; Obesity; Osteoporosis; Vertebrata; Correlation; Mammalia; Diseases of the osteoarticular system; Nutrition disorder; fat mass; Fat; Nutritional status

It was previously believed that obesity and osteoporosis were two unrelated diseases, but recent studies have shown that both diseases share several common genetic and environmental factors. Body fat mass, a component of body weight, is one of the most important indices of obesity, and a substantial...