Hapo-G, haplotype-aware polishing of genome assemblies with accurate reads

• Published in: NAR genomics and bioinformatics Vol. 3; no. 2; p. lqab034
• Main Authors: Aury, Jean-Marc, Istace, Benjamin
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.06.2021
• Subjects: Algorithms; Codons; Diploids; DNA sequencing; Genomes; Haplotypes; Life Sciences; Methart
• ISSN: 2631-9268; 2631-9268
• DOI: 10.1093/nargab/lqab034

Abstract Single-molecule sequencing technologies have recently been commercialized by Pacific Biosciences and Oxford Nanopore with the promise of sequencing long DNA fragments (kilobases to megabases order) and then, using efficient algorithms, provide high quality assemblies in terms of contiguity...