Peripheral Blood circRNA Microarray Profiling Identities hsa_circ_0001831 and hsa_circ_0000867 as Two Novel circRNA Biomarkers for Early Type 2 Diabetic Nephropathy

• Published in: Diabetes, metabolic syndrome and obesity Vol. 15; pp. 2789 - 2801
• Main Authors: Zhang, Keke, Wan, Xinxing, Khan, Md Asaduzzaman, Sun, Xiaoying, Yi, Xuan, Wang, Zhouqi, Chen, Ke, Peng, Lin
• Format: Journal Article
• Language: English
• Published: Macclesfield Dove Medical Press Limited 01.01.2022; Taylor & Francis Ltd; Dove; Dove Medical Press
• Subjects: Age; Analysis; Apoptosis; Biological markers; Biomarkers; Blood pressure; Cholesterol; circrnas microarray; Diabetes; Diabetic nephropathies; Diabetic nephropathy; diagnostic biomarkers; early type 2 diabetic nephropathy; Glucose; Health aspects; Health savings accounts; High density lipoprotein; inflammation; Kidney diseases; Medical diagnosis; Medical research; Medicine, Experimental; MicroRNAs; Ontology; Original Research; Proteins; Software; Thermal cycling; Type 2 diabetes; Variance analysis; China; Taiwan; United States > US

Purpose: Type 2 diabetes mellitus (T2DM) increases the incidence of diabetic nephropathy (DN) and eventually progresses to endstage renal disease. Circular RNAs (circRNAs) are a class of non-coding RNAs that are promising as diagnostic biomarkers and therapeutic targets for human diseases. The aim o...