Association between active cytomegalovirus infection and lung fibroproliferation in adult patients with acute respiratory distress syndrome: a retrospective study

• Published in: BMC infectious diseases Vol. 22; no. 1; pp. 1 - 12
• Main Authors: Zhang, Zhihui, Li, Rujian, Chen, Yubiao, Zhang, Jierong, Zheng, Yongxin, Xu, Minmin, Liang, Jiaqi, Li, Jiahui, Huang, Yongbo, Xu, Yonghao, He, Weiqun, Liu, Xiaoqing, Li, Yimin
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 14.10.2022; BioMed Central; BMC
• Subjects: Acute respiratory distress syndrome; Breastfeeding & lactation; Clinical outcomes; Collagen (type III); Complications and side effects; Computed tomography; Cytomegalovirus; Cytomegalovirus infections; Diagnosis; Fibroproliferation; Fibrosis; High-resolution computer tomography; Infections; Laboratories; Lung diseases; Lungs; Medical records; N-terminal peptide of serum procollagen III; Patients; Preempting; Procollagen; Pulmonary fibrosis; Respiratory distress syndrome; Risk factors; Serology; Statistical analysis; Ventilators; China; United States > US

Cytomegalovirus (CMV) has high seroprevalence, and its active infection is associated with several adverse prognoses in adult patients with acute respiratory distress syndrome (ARDS). However, the role of active CMV infection in ARDS-associated fibroproliferation is unknown. This study aimed at dete...