Motor cortex inhibition and modulation in children with ADHD

• Published in: Neurology Vol. 93; no. 6; p. e599
• Main Authors: Gilbert, Donald L, Huddleston, David A, Wu, Steve W, Pedapati, Ernest V, Horn, Paul S, Hirabayashi, Kathryn, Crocetti, Deanna, Wassermann, Eric M, Mostofsky, Stewart H
• Format: Journal Article
• Language: English
• Published: United States 06.08.2019
• Subjects: Attention Deficit Disorder with Hyperactivity - physiopathology; Attention Deficit Disorder with Hyperactivity - psychology; Case-Control Studies; Child; Child Behavior; Cognition; Evoked Potentials, Motor; Female; Humans; Inhibition, Psychological; Male; Motor Cortex - physiopathology; Motor Skills; Psychomotor Performance; Reaction Time; Transcranial Magnetic Stimulation

Compared to typically developing (TD) peers, children with attention-deficit/hyperactivity disorder (ADHD) consistently demonstrate impaired transcranial magnetic stimulation (TMS)-evoked short interval cortical inhibition (SICI) of motor evoked potentials (MEPs) in resting motor cortex (M1). To det...