Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects - Chen, Dawn; Whitcomb, Randall; MacIntyre, Euan; Tran, Vinh; Do, Zung N; Sabry, James; Patel, Dinesh V; Anandan, Sampath K; Gless, Richard; Webb, Heather K (Journal of clinical pharmacology, 2012)
Keywords: Adamantane - adverse effects; Adamantane - analogs & derivatives; Adamantane - blood; Adamantane - pharmacokinetics; Adult; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epoxide Hydrolases - antagonists & inhibitors; Female; Half-Life; Humans; Male; Middle Aged; Urea - adverse effects; Urea - analogs & derivatives; Urea - blood; Urea - pharmacokinetics; Young Adult