Human intervention study to investigate the intestinal accessibility and bioavailability of anthocyanins from bilberries

• Published in: Food chemistry Vol. 231; pp. 275 - 286
• Main Authors: Mueller, Dolores, Jung, Kathrin, Winter, Manuel, Rogoll, Dorothee, Melcher, Ralph, Richling, Elke
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.09.2017
• Subjects: absorption; Anthocyanins; bilberries; bioactive compounds; Bioavailability; Biological Availability; Colon; Degradation; effluents; Humans; ileum; Metabolism; Plant Extracts; Small intestine; urine; Vaccinium myrtillus; Vaccinium myrtillus L; Del-3,5-diglc; BE; HBAL; HBA; PGAL; Vanillic acid (PubChem CID: 8468); Small intestine; SA; 4-Hydroxybenzaldehyde (PubChem CID: 126); Degradation; Phloroglucinolaldehyde (PubChem CID: 68099); 3-O-Methylgallic acid (PubChem CID: 19829); Cy; Anthocyanins (PubChem CID: 145858); GA; 4-Hydroxybenzoic acid (PubChem CID: 135); MGA; Vaccinium myrtillus L; Del; IS; VA; Bioavailability; Metabolism; PCA; Ara; Gluc; Gal; Protocatechuic acid (PubChem CID: 72); Iso-FA-d3; Mal; Anthocyanins; Gallic acid (PubChem CID: 370); Syringic acid (PubChem CID: 10742); Peo; Pet; Glc

•A human pilot intervention study was performed with volunteers with and without a colon.•High amounts of anthocyanins reach the colon after bilberry intake.•Degradation of anthocyanins plays an important role in the frame of bioavailability.•Colon was a significant site of anthocyanin absorption. W...