Transcriptome analysis reveals SALL4 as a prognostic key gene in gastric adenocarcinoma

• Published in: Journal of Egyptian National Cancer Institute Vol. 34; no. 1; pp. 11 - 8
• Main Authors: Sarma, Ranjan Jyoti, Subbarayan, Sarathbabu, Zohmingthanga, John, Chenkual, Saia, Zomuana, Thomas, Lalruatfela, Sailo Tlau, Pautu, Jeremy L., Maitra, Arindam, Kumar, Nachimuthu Senthil
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 14.03.2022; Springer; Springer Nature B.V; SpringerOpen
• Subjects: Adenocarcinoma; Adenocarcinoma - pathology; Biomarker; Biomarkers; Biotechnology industry; Cancer; Cell adhesion & migration; Comparative analysis; Data processing; Datasets; Development and progression; Differentially expressed genes; Gastric cancer; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes; Genetic aspects; Homeostasis; Humans; Hypotheses; Hypothesis testing; Ligands; Medical prognosis; Medical research; Medicine; Medicine & Public Health; Medicine, Experimental; Oncology; Ontology; Poor survival; Potassium; Principal components analysis; Prognosis; RNA; RNA sequencing; RNA-Seq; Stomach adenocarcinoma; Stomach cancer; Stomach Neoplasms - pathology; Transcription Factors - genetics; United States; India; United States > US; Poor survival; Differentially expressed genes; Biomarker; Stomach adenocarcinoma; RNA-Seq

Background Stomach adenocarcinoma (STAD) dominates 80–90% of gastric cancer (GC). Over the years, it has been realized that the identification of the genes responsible for gastric carcinogenesis is essential to understand the biomarker discovery. Methods This study aims to identify candidate genes f...