fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 105; no. 14; pp. 5638 - 5643
• Main Authors: Ren, Dongtao, Liu, Yidong, Yang, Kwang-Yeol, Han, Ling, Mao, Guohong, Glazebrook, Jane, Zhang, Shuqun
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 08.04.2008; National Acad Sciences
• Subjects: Arabidopsis; Arabidopsis - microbiology; Arabidopsis Proteins - biosynthesis; Arabidopsis thaliana; Biochemical pathways; Biochemistry; Biological Sciences; Biosynthesis; Botany; Botrytis; Botrytis cinerea; camalexin; Cell death; disease resistance; Enzymes; Flowers & plants; Fungi; Fungi - immunology; Gene expression regulation; Gene Expression Regulation, Plant - immunology; Genes; host-pathogen relationships; Infections; Kinases; MAP Kinase Signaling System - immunology; mitogen-activated protein kinase; Mitogen-Activated Protein Kinase 3 - metabolism; Mitogen-Activated Protein Kinase 6 - metabolism; Pathogens; phytoalexins; Plant Diseases - immunology; Proteins; resistance mechanisms; Seedlings; Sesquiterpenes; signal transduction; Terpenes - metabolism

Plant recognition of pathogens leads to rapid activation of MPK3 and MPK6, two Arabidopsis mitogen-activated protein kinases (MAPKs), and their orthologs in other species. Here, we report that synthesis of camalexin, the major phytoalexin in Arabidopsis, is regulated by the MPK3/MPK6 cascade. Activa...