The effects of eating marine- or vegetable-fed farmed trout on the human plasma proteome profiles of healthy men

• Published in: British journal of nutrition Vol. 113; no. 4; pp. 699 - 707
• Main Authors: Rentsch, Maria L., Lametsch, René, Bügel, Susanne, Jessen, Flemming, Lauritzen, Lotte
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.02.2015
• Subjects: Adult; Animal Feed; Animals; Aquaculture; Aquatic Organisms; Biomarkers - blood; Blood; blood proteins; Blood Proteins - analysis; blood sampling; Chickens; chronic exposure; computer software; Denmark; desorption; Diet; Down-Regulation; farmed fish; feed meals; fibrinolysis; Fish; fish consumption; Humans; image analysis; ingestion; Innovative Techniques; Ionization; Male; Meals; Men; Middle Aged; nutritional intervention; Principal Component Analysis; protein synthesis; proteome; Proteome - analysis; Proteomics; Reproducibility of Results; Risk factors; Seafood; silver staining; trout; Trout - growth & development; two-dimensional gel electrophoresis; Up-Regulation; Vegetables; vitamin A; Denmark; Aquaculture fish production; Dietary interventions; n-3 PUFA; Plasma proteomics; Cardiovascular risk

Most human intervention studies have examined the effects on a subset of risk factors, some of which may require long-term exposure. The plasma proteome may reflect the underlying changes in protein expression and activation, and this could be used to identify early risk markers. The aim of the pres...