Localization of a bacterial cytoplasmic receptor is dynamic and changes with cell-cell contacts

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 106; no. 12; pp. 4852 - 4857
• Main Authors: Mauriello, Emilia M.F, Astling, David P, Sliusarenko, Oleksii, Zusman, David R
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 24.03.2009; National Acad Sciences
• Subjects: Bacteria; Bacterial Proteins - chemistry; Bacterial Proteins - metabolism; Biological Sciences; Cell adhesion; Cells; Chemoreception; Chemoreceptors; Chemotaxis; Correlation coefficients; Cytoplasm; Cytoplasm - metabolism; Fluorescence; Gliding; Green Fluorescent Proteins - metabolism; Membranes; Microscopy; Motility; Mutation; Myxococcus xanthus; Myxococcus xanthus - cytology; Myxococcus xanthus - metabolism; Protein Structure, Secondary; Protein Transport; Proteins; Receptors; Receptors, Cell Surface - metabolism; Recombinant Fusion Proteins - metabolism; Signal transduction; Statistical analysis

Directional motility in the gliding bacterium Myxococcus xanthus requires controlled cell reversals mediated by the Frz chemosensory system. FrzCD, a cytoplasmic chemoreceptor, does not form membrane-bound polar clusters typical for most bacteria, but rather cytoplasmic clusters that appear helicall...