Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: A functional imaging study in alcohol dependent subjects - Bach, Patrick; Vollsta¨dt-Klein, Sabine; Kirsch, Martina; Hoffmann, Sabine; Jorde, Anne; Frank, Josef; Charlet, Katrin; Beck, Anne; Heinz, Andreas; Walter, Henrik; Sommer, Wolfgang H.; Spanagel, Rainer; et al. (European neuropsychopharmacology, 2015)
Keywords: Adolescent; Adult; Aged; Alcohol Abstinence; Alcohol-Related Disorders - genetics; Alcohol-Related Disorders - physiopathology; Alcoholism; Brain - physiopathology; Brain Mapping; Cues; Endogenous opioids; Female; fMRI; Follow-Up Studies; Genotyping Techniques; Humans; Internal Medicine; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; OPRM1; Polymorphism, Single Nucleotide; Psychiatry; Receptors, Opioid, mu - genetics; Relapse; Single nucleotide polymorphism; Survival Analysis; Young Adult; fMRI; Endogenous opioids; Relapse; OPRM1; Single nucleotide polymorphism; Alcoholism