Long-Term Muscular Atrophy and Weakness Following Cessation of Botulinum Toxin Type A Injections in the Flexor Digitorum Muscle of Musicians with Focal Hand Dystonia

• Published in: Toxins Vol. 15; no. 4; p. 296
• Main Authors: Ioannou, Christos I., Hodde-Chriske, Franziska L., Altenmüller, Eckart
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2023; MDPI
• Subjects: Asymmetry; Atrophy; Atrophy, Muscular; Botulinum toxin; Botulinum toxin type A; Botulinum Toxins, Type A - adverse effects; Care and treatment; Dosage and administration; Dystonia; Dystonic Disorders - drug therapy; Health aspects; Human subjects; Humans; Injection; muscle thickness; Muscle, Skeletal; Muscles; Muscular Atrophy - chemically induced; Muscular Atrophy - drug therapy; Musicians; Patient outcomes; Patient satisfaction; Recovery; Risk factors; Side effects; strength; symmetry index; Thickness; Toxins; ultrasound; Germany; New Zealand; botulinum toxin; muscle thickness; side effects; symmetry index; strength; ultrasound

The present study assessed muscular atrophy and weakness of the flexor digitorum superficialis (FDS) and profundus (FDP) muscle as possible long-term side effects of botulinum toxin (BoNT) injections in hand dystonia patients after the termination of their treatment. For the assessment of both param...