An attenuated vaccinia vaccine encoding the severe acute respiratory syndrome coronavirus-2 spike protein elicits broad and durable immune responses, and protects cynomolgus macaques and human angiotensin-converting enzyme 2 transgenic mice from severe acute respiratory syndrome coronavirus-2 and its variants - Ishigaki, Hirohito; Yasui, Fumihiko; Nakayama, Misako; Endo, Akinori; Yamamoto, Naoki; Yamaji, Kenzaburo; Nguyen, Cong Thanh; Kitagawa, Yoshinori; Sanada, Takahiro; Honda, Tomoko; Munakata, Tsubasa; Higa, Masahiko; et al. (Frontiers in microbiology, 2022)
Keywords: animal model; broad immune response; DIs-based SARS-CoV-2 vaccine; durable immune response; Microbiology; SARS-CoV-2; SARS-CoV-2 variants