Chronic adult primary immune thrombocytopenia (ITP) in the Asia-Pacific region

• Published in: International journal of hematology Vol. 94; no. 2; pp. 142 - 149
• Main Authors: Heng, Lee Lai, Caguioa, Priscilla, Chin, Ng Soo, Chiou, Tzeon-Jye, Lee, Jong Wook, Miyakawa, Yoshitaka, Tambunan, Karmel L., Chong, Beng H.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Tokyo Springer Japan 01.08.2011; Springer; Springer Nature B.V
• Subjects: Adult; Asia - epidemiology; Asia - ethnology; Biological and medical sciences; Ethnic Groups; Far East - epidemiology; Far East - ethnology; Helicobacter pylori; Hematologic and hematopoietic diseases; Hematology; Humans; Medical sciences; Medicine; Medicine & Public Health; Oncology; Platelet diseases and coagulopathies; Practice Guidelines as Topic; Purpura, Thrombocytopenic, Idiopathic - diagnosis; Purpura, Thrombocytopenic, Idiopathic - epidemiology; Purpura, Thrombocytopenic, Idiopathic - ethnology; Purpura, Thrombocytopenic, Idiopathic - therapy; Review Article; Asia; Far East; Asia-Pacific region; Primary immune thrombocytopenia (ITP); Human; Thrombocytopenia; Chronic; Platelet; Hematology; Primary; Adult; Hemopathy; Immune thrombocytopenic purpura
• ISSN: 0925-5710; 1865-3774
• DOI: 10.1007/s12185-011-0894-8

Patients with primary immune thrombocytopenia (ITP) from the Asia-Pacific region often exhibit characteristics distinct from those of patients from the West. Moreover, as the region itself is heterogeneous, the ITP landscape among individual Asia-Pacific countries can be diverse. The recently released international consensus report on ITP places new emphasis on ITP, but does not address the unique ITP landscape in the Asia-Pacific region, which is home to 60% of the world’s population. In an attempt to characterize how the ITP landscape differs between the West and the Asia-Pacific region, an expert panel with representatives from Northeast Asia, Southeast Asia, and Australia was convened. Important differences were identified between the guidance provided in the international consensus report and experience in the Asia-Pacific region, namely diagnostic practices, incidence and approach to ITP secondary to H. pylori infection, systemic lupus erythematosus-related ITP, the use of bone marrow examination, initial treatment strategies, and the role of splenectomy, rituximab, and thrombopoietin receptor agonists.