Cell cycle regulation of the psoriasis associated gene CCHCR1 by transcription factor E2F1

• Published in: PloS one Vol. 18; no. 12; p. e0294661
• Main Authors: Ling, Yick Hin, Chen, Yingying, Leung, Kwok Nam, Chan, King Ming, Liu, W K
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.12.2023
• Subjects: Alopecia; Baldness; Biology and Life Sciences; Cell cycle; Centrosomes; COVID-19; Diabetes; Diagnosis; Evaluation; Gene expression; Gene regulation; Genes; Genetic aspects; Protein structure; Psoriasis; Regulatory sequences; Research and Analysis Methods; Skin diseases; Transcription factors; Hong Kong

The coiled-coil alpha-helical rod protein 1 (CCHCR1) was first identified as a candidate gene in psoriasis and has lately been found to be associated with a wide range of clinical conditions including COVID-19. CCHCR1 is located within P-bodies and centrosomes, but its exact role in these two subcel...