Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation - Yokoyama, Shigetoshi; Koo, Imhoi; Aibara, Daisuke; Tian, Yuan; Murray, Iain A.; Collins, Stephanie L.; Coslo, Denise M.; Kono, Mari; Peters, Jeffrey M.; Proia, Richard L.; Gonzalez, Frank J.; Perdew, Gary H.; et al. (Advanced science, 2024)
Keywords: AHR; Amino acids; Animals; Basic Helix-Loop-Helix Transcription Factors - genetics; Basic Helix-Loop-Helix Transcription Factors - metabolism; Cell Nucleus - metabolism; ceramide; CRISPR; Cytochrome P-450 CYP1A1 - genetics; Cytochrome P-450 CYP1A1 - metabolism; Cytoplasm; Dioxins; Enzymes; Gene expression; Humans; Hydrocarbons; Kinases; Ligands; Localization; Metabolism; Mice; Phosphotransferases (Alcohol Group Acceptor) - genetics; Phosphotransferases (Alcohol Group Acceptor) - metabolism; Promoter Regions, Genetic - genetics; Proteins; Receptors, Aryl Hydrocarbon - genetics; Receptors, Aryl Hydrocarbon - metabolism; sphingolipid; Sphingosine - analogs & derivatives; Sphingosine - metabolism; SPHK2; ceramide; AHR; SPHK2; sphingolipid