Regulation of the xcp secretion pathway by multiple quorum‐sensing modulons in Pseudomonas aeruginosa

• Published in: Molecular microbiology Vol. 24; no. 6; pp. 1169 - 1178
• Main Authors: Chapon‐Hervé, Virginie, Akrim, Mohammed, Latifi, Amel, Williams, Paul, Lazdunski, Andrée, Bally, Marc
• Format: Journal Article
• Language: English
• Published: Oxford UK Blackwell Science Ltd 01.06.1997; Wiley
• Subjects: Bacterial Proteins - genetics; Bacterial Proteins - metabolism; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Escherichia coli; Gene Expression Regulation, Bacterial; Life Sciences; Membrane Transport Proteins; Pseudomonas aeruginosa; Pseudomonas aeruginosa - genetics; Recombinant Fusion Proteins - genetics; Trans-Activators - genetics; Trans-Activators - metabolism; pseudomonas aeruginosa; type II secretion system; quorum sensing

The virulence of the opportunistic pathogen Pseudomonas aeruginosa is largely dependent upon the extracellular production of a number of secreted proteins with toxic or degradative activities. The synthesis of several exoenzymes is controlled in a cell‐density‐dependent manner by two interlinked quo...