Microinfusion of a Corticotrophin-Releasing Hormone Receptor 1 Antisense Oligodeoxynucleotide into the Dorsal Hippocampus Attenuates Stress Responses at Specific Times After Stress Exposure - Kozlovsky, N.; Zohar, J.; Kaplan, Z.; Cohen, H. (Journal of neuroendocrinology, 2012)
Keywords: Acoustic startle response; Adult and adolescent clinical studies; animal model; Animals; antisense oligodeoxynucleotide; Anxiety disorders. Neuroses; Biological and medical sciences; Blotting, Western; brain-derived neurotrophic factor; Brain-Derived Neurotrophic Factor - metabolism; corticotrophin-releasing hormone; Extracellular Signal-Regulated MAP Kinases - metabolism; Fundamental and applied biological sciences. Psychology; Hippocampus - enzymology; Hippocampus - metabolism; Hippocampus - physiology; Male; Medical sciences; Oligonucleotides, Antisense - administration & dosage; Post-traumatic stress disorder; posttraumatic stress disorder; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone - genetics; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Stress, Physiological; Vertebrates: endocrinology; corticotrophin-releasing hormone; Animal model; Central nervous system; Anxiety disorder; Corticotropin releasing factor; Posttraumatic stress disorder; Stress; Encephalon; antisense oligodeoxynucleotide; Hypothalamic hormone; Corticorelin; Analog; Brain derived neurotrophic factor; brain-derived neurotrophic factor; Hormone releasing factor; Hippocampus; Biological receptor