International Incidence and Outcomes of Biliary Atresia

ABSTRACT Objectives: International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population‐based literature to assess international variation of BA incidence and outcomes, and to assess the evid...

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Published inJournal of pediatric gastroenterology and nutrition Vol. 56; no. 4; pp. 344 - 354
Main Authors Jimenez‐Rivera, Carolina, Jolin‐Dahel, Kheira S., Fortinsky, Kyle J., Gozdyra, Peter, Benchimol, Eric I.
Format Journal Article
LanguageEnglish
Published Hagerstown, MD Copyright by ESPGHAN and NASPGHAN 01.04.2013
Lippincott Williams & Wilkins
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Abstract ABSTRACT Objectives: International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population‐based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in incidence, centralization of Kasai hepatoportoenterostomy, and newborn screening. Methods: We conducted a systematic review (registration number CRD42011001441) of observational or interventional research within MEDLINE, EMBASE, and the Cochrane Database, which reported incidence, prevalence, or outcomes of infants with BA. Population‐based studies, defined by inclusion of an entire population or representative sample, were included. Outcomes included overall survival, native liver survival (NLS), and time to Kasai hepatoportoenterostomy. Single‐ or multicenter studies were excluded unless those centers captured all potential patients within a jurisdiction. Two independent data extractors reviewed the s and articles. Results: A total of 40 studies were included following review of 3128 references. A wide range of incidence was reported internationally. Ten‐year overall survival ranged from 66.7% to 89%. NLS ranged from 20.3% to 75.8% at 1 to 3 years and 24% to 52.8% at 10 years. Earlier age at Kasai was a predictor of improved NLS. Seasonality was reported in 11 studies, and 3 reported an increased incidence during the months of August to March. The evidence for centralization of Kasai to high‐volume centers is promising but does not account for all case‐mix, provider, or health system factors involved in volume–outcome relations. Stool color card screening resulted in earlier Kasai and improved NLS in Taiwan. Conclusions: Large, international studies could help fill the gaps in knowledge identified by this review.
AbstractList OBJECTIVES:International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population-based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in incidence, centralization of Kasai hepatoportoenterostomy, and newborn screening. METHODS:We conducted a systematic review (registration number CRD42011001441) of observational or interventional research within MEDLINE, EMBASE, and the Cochrane Database, which reported incidence, prevalence, or outcomes of infants with BA. Population-based studies, defined by inclusion of an entire population or representative sample, were included. Outcomes included overall survival, native liver survival (NLS), and time to Kasai hepatoportoenterostomy. Single- or multicenter studies were excluded unless those centers captured all potential patients within a jurisdiction. Two independent data extractors reviewed the abstracts and articles. RESULTS:A total of 40 studies were included following review of 3128 references. A wide range of incidence was reported internationally. Ten-year overall survival ranged from 66.7% to 89%. NLS ranged from 20.3% to 75.8% at 1 to 3 years and 24% to 52.8% at 10 years. Earlier age at Kasai was a predictor of improved NLS. Seasonality was reported in 11 studies, and 3 reported an increased incidence during the months of August to March. The evidence for centralization of Kasai to high-volume centers is promising but does not account for all case-mix, provider, or health system factors involved in volume–outcome relations. Stool color card screening resulted in earlier Kasai and improved NLS in Taiwan. CONCLUSIONS:Large, international studies could help fill the gaps in knowledge identified by this review.
ABSTRACT Objectives: International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population‐based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in incidence, centralization of Kasai hepatoportoenterostomy, and newborn screening. Methods: We conducted a systematic review (registration number CRD42011001441) of observational or interventional research within MEDLINE, EMBASE, and the Cochrane Database, which reported incidence, prevalence, or outcomes of infants with BA. Population‐based studies, defined by inclusion of an entire population or representative sample, were included. Outcomes included overall survival, native liver survival (NLS), and time to Kasai hepatoportoenterostomy. Single‐ or multicenter studies were excluded unless those centers captured all potential patients within a jurisdiction. Two independent data extractors reviewed the s and articles. Results: A total of 40 studies were included following review of 3128 references. A wide range of incidence was reported internationally. Ten‐year overall survival ranged from 66.7% to 89%. NLS ranged from 20.3% to 75.8% at 1 to 3 years and 24% to 52.8% at 10 years. Earlier age at Kasai was a predictor of improved NLS. Seasonality was reported in 11 studies, and 3 reported an increased incidence during the months of August to March. The evidence for centralization of Kasai to high‐volume centers is promising but does not account for all case‐mix, provider, or health system factors involved in volume–outcome relations. Stool color card screening resulted in earlier Kasai and improved NLS in Taiwan. Conclusions: Large, international studies could help fill the gaps in knowledge identified by this review.
OBJECTIVESInternational trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population-based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in incidence, centralization of Kasai hepatoportoenterostomy, and newborn screening.METHODSWe conducted a systematic review (registration number CRD42011001441) of observational or interventional research within MEDLINE, EMBASE, and the Cochrane Database, which reported incidence, prevalence, or outcomes of infants with BA. Population-based studies, defined by inclusion of an entire population or representative sample, were included. Outcomes included overall survival, native liver survival (NLS), and time to Kasai hepatoportoenterostomy. Single- or multicenter studies were excluded unless those centers captured all potential patients within a jurisdiction. Two independent data extractors reviewed the abstracts and articles.RESULTSA total of 40 studies were included following review of 3128 references. A wide range of incidence was reported internationally. Ten-year overall survival ranged from 66.7% to 89%. NLS ranged from 20.3% to 75.8% at 1 to 3 years and 24% to 52.8% at 10 years. Earlier age at Kasai was a predictor of improved NLS. Seasonality was reported in 11 studies, and 3 reported an increased incidence during the months of August to March. The evidence for centralization of Kasai to high-volume centers is promising but does not account for all case-mix, provider, or health system factors involved in volume-outcome relations. Stool color card screening resulted in earlier Kasai and improved NLS in Taiwan.CONCLUSIONSLarge, international studies could help fill the gaps in knowledge identified by this review.
International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population-based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in incidence, centralization of Kasai hepatoportoenterostomy, and newborn screening. We conducted a systematic review (registration number CRD42011001441) of observational or interventional research within MEDLINE, EMBASE, and the Cochrane Database, which reported incidence, prevalence, or outcomes of infants with BA. Population-based studies, defined by inclusion of an entire population or representative sample, were included. Outcomes included overall survival, native liver survival (NLS), and time to Kasai hepatoportoenterostomy. Single- or multicenter studies were excluded unless those centers captured all potential patients within a jurisdiction. Two independent data extractors reviewed the abstracts and articles. A total of 40 studies were included following review of 3128 references. A wide range of incidence was reported internationally. Ten-year overall survival ranged from 66.7% to 89%. NLS ranged from 20.3% to 75.8% at 1 to 3 years and 24% to 52.8% at 10 years. Earlier age at Kasai was a predictor of improved NLS. Seasonality was reported in 11 studies, and 3 reported an increased incidence during the months of August to March. The evidence for centralization of Kasai to high-volume centers is promising but does not account for all case-mix, provider, or health system factors involved in volume-outcome relations. Stool color card screening resulted in earlier Kasai and improved NLS in Taiwan. Large, international studies could help fill the gaps in knowledge identified by this review.
Author Jolin‐Dahel, Kheira S.
Fortinsky, Kyle J.
Jimenez‐Rivera, Carolina
Gozdyra, Peter
Benchimol, Eric I.
AuthorAffiliation Division of Gastroenterology, Hepatology and Nutrition, Childrenʼs Hospital of Eastern Ontario, Ottawa, ON, Canada †Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
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  surname: Jimenez‐Rivera
  fullname: Jimenez‐Rivera, Carolina
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  givenname: Kheira S.
  surname: Jolin‐Dahel
  fullname: Jolin‐Dahel, Kheira S.
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  givenname: Kyle J.
  surname: Fortinsky
  fullname: Fortinsky, Kyle J.
  organization: Children's Hospital of Eastern Ontario
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  givenname: Eric I.
  surname: Benchimol
  fullname: Benchimol, Eric I.
  organization: Children's Hospital of Eastern Ontario
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Cites_doi 10.1097/00004836-199606000-00010
10.1111/j.1478-3231.2011.02578.x
10.1542/peds.2011-0742
10.1002/hep.510300330
10.1542/peds.2011-1869
10.1136/bmj.290.6465.345
10.1002/hep.20547
10.1002/j.1536-4801.2002.tb07807.x
10.1620/tjem.181.85
10.1016/0022-3468(95)90062-4
10.1542/peds.99.3.376
10.1111/j.1365-3016.2003.00536.x
10.1016/j.jpeds.2005.12.054
10.1002/hep.24023
10.1016/j.jpeds.2006.05.030
10.1136/jech.53.4.235
10.1016/S0022-3476(82)80576-3
10.1016/j.jpedsurg.2011.04.013
10.3109/00365521.2011.627446
10.1016/j.jclinepi.2008.10.012
10.1542/peds.2005-1267
10.1007/BF01655504
10.1002/hep.22182
10.1016/j.cgh.2011.07.024
10.1093/oxfordjournals.epirev.a017974
10.1097/MPG.0b013e31817d80de
10.1016/0022-3468(94)90731-5
10.1016/S0140-6736(99)03492-3
10.1016/j.jpeds.2010.09.061
10.1016/S0022-3476(96)70260-3
10.1007/s00431-010-1266-8
10.1016/S0022-3468(03)00178-7
10.1136/adc.56.8.622
10.1016/j.jpeds.2007.05.051
10.1016/S0168-8278(99)80312-2
10.1056/NEJM198208193070806
10.1111/j.1440-1746.2007.05114.x
10.1016/S0140-6736(04)16045-5
10.1136/adc.2009.159780
10.1016/j.jpedsurg.2007.08.035
10.1055/s-0030-1268476
10.1542/peds.2010-3495
10.1097/MPG.0b013e3181633562
10.1136/bmj.319.7208.471
10.1002/hep.21219
10.1067/mpd.2002.126001
10.1016/0022-3468(90)90222-U
10.1016/S0022-3476(84)80076-1
10.1542/peds.2008-1949
10.1097/MPG.0b013e3181d67e5e
10.1007/BF00436755
10.1067/mpd.2001.111276
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Issue 4
Keywords Human
Pediatrics
Biliary atresia
screening
Prognosis
Metabolic diseases
Medical screening
Epidemiology
Incidence
outcomes
Gastroenterology
Digestive diseases
Child
Liver transplantation
Language English
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E.I.B. was supported by a Career Development Award from the Canadian Child Health Clinician Scientist Program.
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PublicationDate 2013-April
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  text: 2013-April
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PublicationTitle Journal of pediatric gastroenterology and nutrition
PublicationTitleAlternate J Pediatr Gastroenterol Nutr
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References 1995; 30
2004; 363
2011; 158
1985; 290
1982; 307
2011; 53
1982; 100
1994; 29
2009; 48
2011; 128
1997; 99
2009; 94
2002; 141
1988; 43
2008; 23
2009; 123
2011; 21
1999; 53
2001; 138
1996; 22
2009; 62
2000; 355
2010; 169
2002; 35
1968; 102
1984; 105
2011; 31
2005; 41
1988; 12
2003; 38
1997; 181
1998; 20
2006; 117
1996; 129
2011; 9
2010; 86
1990; 25
2004; 18
2007; 151
2006; 44
2008; 47
2008; 46
1994; 13
1999; 31
2011; 46
1999; 30
2007; 42
1994; 1
2012; 47
2006; 149
2006; 148
1999; 319
2010; 51
1981; 56
23799456 - J Pediatr Gastroenterol Nutr. 2013 Sep;57(3):e20
23799455 - J Pediatr Gastroenterol Nutr. 2013 Sep;57(3):e19-20
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Houwen RH (e_1_2_8_28_1) 1988; 43
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References_xml – volume: 355
  start-page: 25
  year: 2000
  end-page: 29
  article-title: The frequency and outcome of biliary atresia in the UK and Ireland
  publication-title: Lancet
– volume: 149
  start-page: 393
  year: 2006
  end-page: 400
  article-title: The biliary atresia splenic malformation syndrome: a 28‐year single‐center retrospective study
  publication-title: J Pediatr
– volume: 105
  start-page: 912
  year: 1984
  end-page: 915
  article-title: Role of reovirus type 3 in persistent infantile cholestasis
  publication-title: J Pediatr
– volume: 47
  start-page: 1233
  year: 2008
  end-page: 1240
  article-title: Universal screening for biliary atresia using an infant stool color card in Taiwan
  publication-title: Hepatology
– volume: 35
  start-page: S89
  issue: suppl 2
  year: 2002
  end-page: S97
  article-title: Cholestatic liver disease: Working group report of the first World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
  publication-title: J Pediatr Gastroenterol Nutr
– volume: 363
  start-page: 1354
  year: 2004
  end-page: 1357
  article-title: Seamless management of biliary atresia in England and Wales (1999‐2002)
  publication-title: Lancet
– volume: 43
  start-page: 68
  year: 1988
  end-page: 71
  article-title: Time‐space distribution of extrahepatic biliary atresia in The Netherlands and West Germany
  publication-title: Z Kinderchir
– volume: 38
  start-page: 997
  year: 2003
  end-page: 1000
  article-title: Five‐ and 10‐year survival rates after surgery for biliary atresia: a report from the Japanese Biliary Atresia Registry
  publication-title: J Pediatr Surg
– volume: 290
  start-page: 345
  year: 1985
  end-page: 347
  article-title: Results of surgical treatment for extrahepatic biliary atresia in United Kingdom 1980‐2. Survey conducted on behalf of the British Paediatric Association Gastroenterology Group and the British Association of Paediatric Surgeons
  publication-title: Br Med J (Clin Res Ed)
– volume: 21
  start-page: 82
  year: 2011
  end-page: 87
  article-title: Biliary atresia: lessons learned from the voluntary German registry
  publication-title: Eur J Pediatr Surg
– volume: 151
  start-page: 659
  year: 2007
  end-page: 665.e1
  article-title: Biliary atresia: the Canadian experience
  publication-title: J Pediatr
– volume: 47
  start-page: 99
  year: 2012
  end-page: 107
  article-title: National centralization of biliary atresia care to an assigned multidisciplinary team provides high‐quality outcomes
  publication-title: Scand J Gastroenterol
– volume: 62
  start-page: 944
  year: 2009
  end-page: 952
  article-title: An evidence‐based practice guideline for the peer review of electronic search strategies
  publication-title: J Clin Epidemiol
– volume: 20
  start-page: 81
  year: 1998
  end-page: 90
  article-title: Population‐based cohort studies
  publication-title: Epidemiol Rev
– volume: 86
  start-page: 473
  year: 2010
  end-page: 479
  article-title: Biliary atresia: the Brazilian experience
  publication-title: J Pediatr
– volume: 99
  start-page: 376
  year: 1997
  end-page: 382
  article-title: Epidemiology of biliary atresia: a population‐based study
  publication-title: Pediatrics
– volume: 307
  start-page: 481
  year: 1982
  end-page: 484
  article-title: Biliary atresia and reovirus type 3 infection
  publication-title: N Engl J Med
– volume: 123
  start-page: 1280
  year: 2009
  end-page: 1286
  article-title: Impact of age at Kasai operation on its results in late childhood and adolescence: a rational basis for biliary atresia screening
  publication-title: Pediatrics
– volume: 169
  start-page: 1529
  year: 2010
  end-page: 1534
  article-title: Biliary atresia: the Croatian experience 1992‐1996
  publication-title: Eur J Pediatr
– volume: 1
  start-page: 646
  year: 1994
  end-page: 651
  article-title: [Biliary atresia in French Polynesia. Retrospective study of 10 years]
  publication-title: Arch Pediatr
– volume: 22
  start-page: 292
  year: 1996
  end-page: 294
  article-title: Lack of evidence for seasonal variation in extrahepatic biliary atresia during infancy
  publication-title: J Clin Gastroenterol
– volume: 48
  start-page: 78
  year: 2009
  end-page: 81
  article-title: British paediatric surveillance unit study of biliary atresia: outcome at 13 years
  publication-title: J Pediatr Gastroenterol Nutr
– volume: 128
  start-page: e1428
  year: 2011
  end-page: e1433
  article-title: Patients with biliary atresia have elevated direct/conjugated bilirubin levels shortly after birth
  publication-title: Pediatrics
– volume: 129
  start-page: 306
  year: 1996
  end-page: 308
  article-title: Direct enzymatic assay of urinary sulfated bile acids to replace serum bilirubin testing for selective screening of neonatal cholestasis
  publication-title: J Pediatr
– volume: 128
  start-page: e530
  year: 2011
  end-page: e536
  article-title: Decreasing rate of biliary atresia in Taiwan: a survey, 2004‐2009
  publication-title: Pediatrics
– volume: 9
  start-page: 1086
  year: 2011
  end-page: 1091
  article-title: Twenty‐year transplant‐free survival rate among patients with biliary atresia
  publication-title: Clin Gastroenterol Hepatol
– volume: 23
  start-page: 62
  year: 2008
  end-page: 66
  article-title: Epidemiological features of biliary atresia in Taiwan, a national study 1996‐2003
  publication-title: J Gastroenterol Hepatol
– volume: 51
  start-page: 61
  year: 2010
  end-page: 65
  article-title: Biliary atresia in Canada: the effect of centre caseload experience on outcome
  publication-title: J Pediatr Gastroenterol Nutr
– volume: 31
  start-page: 1485
  year: 2011
  end-page: 1493
  article-title: Biliary atresia with associated structural malformations in Canadian infants
  publication-title: Liver Int
– volume: 13
  start-page: 1
  year: 1994
  end-page: 5
  article-title: Epidemiological and clinical study of the aetiology of cholestatic syndrome in infancy in Serbia
  publication-title: Arch Gastroenterohepatol
– volume: 102
  start-page: 275
  year: 1968
  end-page: 288
  article-title: [Incidence of congenital biliary atresia]
  publication-title: Z Kinderheilkd
– volume: 100
  start-page: 749
  year: 1982
  end-page: 753
  article-title: Studies in the etiology of extrahepatic biliary atresia: time‐space clustering
  publication-title: J Pediatr
– volume: 42
  start-page: 2090
  year: 2007
  end-page: 2092
  article-title: Insignificant seasonal and geographical variation in incidence of biliary atresia in Japan: a regional survey of over 20 years
  publication-title: J Pediatr Surg
– volume: 117
  start-page: 1147
  year: 2006
  end-page: 1154
  article-title: Screening for biliary atresia by infant stool color card in Taiwan
  publication-title: Pediatrics
– volume: 141
  start-page: 217
  year: 2002
  end-page: 222
  article-title: A population‐based study on the incidence and possible pre‐ and perinatal etiologic risk factors of biliary atresia
  publication-title: J Pediatr
– volume: 44
  start-page: 75
  year: 2006
  end-page: 84
  article-title: Management of patients with biliary atresia in France: results of a decentralized policy 1986‐2002
  publication-title: Hepatology
– volume: 158
  start-page: 562
  year: 2011
  end-page: 565
  article-title: Interpreting conjugated bilirubin levels in newborns
  publication-title: J Pediatr
– volume: 46
  start-page: 299
  year: 2008
  end-page: 307
  article-title: Biliary atresia: Swiss national study, 1994‐2004
  publication-title: J Pediatr Gastroenterol Nutr
– volume: 181
  start-page: 85
  year: 1997
  end-page: 95
  article-title: Japanese Biliary Atresia Registry, 1989 to 1994
  publication-title: Tohoku J Exp Med
– volume: 12
  start-page: 871
  year: 1988
  end-page: 874
  article-title: A history of the Kasai operation: hepatic portoenterostomy for biliary atresia
  publication-title: World J Surg
– volume: 148
  start-page: 467
  year: 2006
  end-page: 474
  article-title: A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000
  publication-title: J Pediatr
– volume: 41
  start-page: 366
  year: 2005
  end-page: 371
  article-title: Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liver
  publication-title: Hepatology
– volume: 29
  start-page: 645
  year: 1994
  end-page: 647
  article-title: Use of near infrared reflectance spectroscopy in the screening for biliary atresia
  publication-title: J Pediatr Surg
– volume: 138
  start-page: 224
  year: 2001
  end-page: 228
  article-title: Is the Kasai operation still indicated in children older than 3 months diagnosed with biliary atresia
  publication-title: J Pediatr
– volume: 56
  start-page: 622
  year: 1981
  end-page: 627
  article-title: Cholestatic jaundice in infancy. The importance of familial and genetic factors in aetiology and prognosis
  publication-title: Arch Dis Child
– volume: 18
  start-page: 97
  year: 2004
  end-page: 105
  article-title: The epidemiology of extrahepatic biliary atresia in New York State, 1983‐98
  publication-title: Paediatr Perinat Epidemiol
– volume: 46
  start-page: 1689
  year: 2011
  end-page: 1694
  article-title: Biliary atresia in England and Wales: results of centralization and new benchmark
  publication-title: J Pediatr Surg
– volume: 25
  start-page: 1076
  year: 1990
  end-page: 1080
  article-title: Biliary atresia registry, 1976 to 1989
  publication-title: J Pediatr Surg
– volume: 94
  start-page: F451
  year: 2009
  end-page: F455
  article-title: Epidemiology of biliary atresia in England and Wales (1999‐2006)
  publication-title: Arch Dis Child Fetal Neonatal Ed
– volume: 31
  start-page: 1006
  year: 1999
  end-page: 1013
  article-title: Epidemiology of biliary atresia in France: a national study 1986‐96
  publication-title: J Hepatol
– volume: 128
  start-page: e1209
  year: 2011
  end-page: e1215
  article-title: Stool color card screening for biliary atresia
  publication-title: Pediatrics
– volume: 30
  start-page: 485
  year: 1995
  end-page: 487
  article-title: Biliary atresia and the polysplenia syndrome: its impact on final outcome
  publication-title: J Pediatr Surg
– volume: 53
  start-page: 235
  year: 1999
  end-page: 238
  article-title: Studying seasonality by using sine and cosine functions in regression analysis
  publication-title: J Epidemiol Community Health
– volume: 53
  start-page: 202
  year: 2011
  end-page: 208
  article-title: Effects of the infant stool color card screening program on 5‐year outcome of biliary atresia in Taiwan
  publication-title: Hepatology
– volume: 319
  start-page: 471
  year: 1999
  end-page: 477
  article-title: Screening of newborn infants for cholestatic hepatobiliary disease with tandem mass spectrometry
  publication-title: BMJ
– volume: 30
  start-page: 606
  year: 1999
  end-page: 611
  article-title: Prognosis of biliary atresia in the era of liver transplantation: French national study from 1986 to 1996
  publication-title: Hepatology
– ident: e_1_2_8_45_1
  doi: 10.1097/00004836-199606000-00010
– ident: e_1_2_8_51_1
  doi: 10.1111/j.1478-3231.2011.02578.x
– ident: e_1_2_8_32_1
  doi: 10.1542/peds.2011-0742
– ident: e_1_2_8_24_1
  doi: 10.1002/hep.510300330
– ident: e_1_2_8_58_1
  doi: 10.1542/peds.2011-1869
– volume: 13
  start-page: 1
  year: 1994
  ident: e_1_2_8_30_1
  article-title: Epidemiological and clinical study of the aetiology of cholestatic syndrome in infancy in Serbia
  publication-title: Arch Gastroenterohepatol
  contributor:
    fullname: Perisic VN
– ident: e_1_2_8_10_1
  doi: 10.1136/bmj.290.6465.345
– ident: e_1_2_8_52_1
  doi: 10.1002/hep.20547
– ident: e_1_2_8_2_1
  doi: 10.1002/j.1536-4801.2002.tb07807.x
– ident: e_1_2_8_56_1
  doi: 10.1620/tjem.181.85
– ident: e_1_2_8_50_1
  doi: 10.1016/0022-3468(95)90062-4
– ident: e_1_2_8_26_1
  doi: 10.1542/peds.99.3.376
– ident: e_1_2_8_21_1
  doi: 10.1111/j.1365-3016.2003.00536.x
– volume: 43
  start-page: 68
  year: 1988
  ident: e_1_2_8_28_1
  article-title: Time‐space distribution of extrahepatic biliary atresia in The Netherlands and West Germany
  publication-title: Z Kinderchir
  contributor:
    fullname: Houwen RH
– ident: e_1_2_8_48_1
  doi: 10.1016/j.jpeds.2005.12.054
– ident: e_1_2_8_7_1
  doi: 10.1002/hep.24023
– ident: e_1_2_8_49_1
  doi: 10.1016/j.jpeds.2006.05.030
– ident: e_1_2_8_46_1
  doi: 10.1136/jech.53.4.235
– ident: e_1_2_8_33_1
  doi: 10.1016/S0022-3476(82)80576-3
– ident: e_1_2_8_34_1
  doi: 10.1016/j.jpedsurg.2011.04.013
– ident: e_1_2_8_35_1
  doi: 10.3109/00365521.2011.627446
– ident: e_1_2_8_12_1
  doi: 10.1016/j.jclinepi.2008.10.012
– ident: e_1_2_8_20_1
  doi: 10.1542/peds.2005-1267
– ident: e_1_2_8_47_1
  doi: 10.1007/BF01655504
– ident: e_1_2_8_16_1
  doi: 10.1002/hep.22182
– ident: e_1_2_8_41_1
  doi: 10.1016/j.cgh.2011.07.024
– ident: e_1_2_8_13_1
  doi: 10.1093/oxfordjournals.epirev.a017974
– volume: 1
  start-page: 646
  year: 1994
  ident: e_1_2_8_27_1
  article-title: [Biliary atresia in French Polynesia. Retrospective study of 10 years]
  publication-title: Arch Pediatr
  contributor:
    fullname: Vic P
– ident: e_1_2_8_8_1
  doi: 10.1097/MPG.0b013e31817d80de
– ident: e_1_2_8_11_1
– ident: e_1_2_8_54_1
  doi: 10.1016/0022-3468(94)90731-5
– ident: e_1_2_8_9_1
  doi: 10.1016/S0140-6736(99)03492-3
– ident: e_1_2_8_57_1
  doi: 10.1016/j.jpeds.2010.09.061
– ident: e_1_2_8_53_1
  doi: 10.1016/S0022-3476(96)70260-3
– ident: e_1_2_8_15_1
  doi: 10.1007/s00431-010-1266-8
– ident: e_1_2_8_22_1
  doi: 10.1016/S0022-3468(03)00178-7
– ident: e_1_2_8_31_1
  doi: 10.1136/adc.56.8.622
– ident: e_1_2_8_3_1
  doi: 10.1016/j.jpeds.2007.05.051
– ident: e_1_2_8_25_1
  doi: 10.1016/S0168-8278(99)80312-2
– ident: e_1_2_8_44_1
  doi: 10.1056/NEJM198208193070806
– volume: 86
  start-page: 473
  year: 2010
  ident: e_1_2_8_6_1
  article-title: Biliary atresia: the Brazilian experience
  publication-title: J Pediatr
  contributor:
    fullname: Carvalho E
– ident: e_1_2_8_5_1
  doi: 10.1111/j.1440-1746.2007.05114.x
– ident: e_1_2_8_42_1
  doi: 10.1016/S0140-6736(04)16045-5
– ident: e_1_2_8_4_1
  doi: 10.1136/adc.2009.159780
– ident: e_1_2_8_18_1
  doi: 10.1016/j.jpedsurg.2007.08.035
– ident: e_1_2_8_14_1
  doi: 10.1055/s-0030-1268476
– ident: e_1_2_8_36_1
  doi: 10.1542/peds.2010-3495
– ident: e_1_2_8_17_1
  doi: 10.1097/MPG.0b013e3181633562
– ident: e_1_2_8_55_1
  doi: 10.1136/bmj.319.7208.471
– ident: e_1_2_8_19_1
  doi: 10.1002/hep.21219
– ident: e_1_2_8_23_1
  doi: 10.1067/mpd.2002.126001
– ident: e_1_2_8_40_1
  doi: 10.1016/0022-3468(90)90222-U
– ident: e_1_2_8_43_1
  doi: 10.1016/S0022-3476(84)80076-1
– ident: e_1_2_8_39_1
  doi: 10.1542/peds.2008-1949
– ident: e_1_2_8_37_1
  doi: 10.1097/MPG.0b013e3181d67e5e
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  doi: 10.1007/BF00436755
– ident: e_1_2_8_38_1
  doi: 10.1067/mpd.2001.111276
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Snippet ABSTRACT Objectives: International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported...
OBJECTIVES:International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide....
International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We...
OBJECTIVESInternational trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide....
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SubjectTerms biliary atresia
Biliary Atresia - diagnosis
Biliary Atresia - epidemiology
Biliary Atresia - physiopathology
Biliary Atresia - therapy
Biological and medical sciences
Child
epidemiology
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
Global Health
Humans
Incidence
liver transplantation
Liver, biliary tract, pancreas, portal circulation, spleen
Medical sciences
outcomes
pediatrics
Prognosis
Referral and Consultation
screening
Seasons
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Survival Analysis
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Title International Incidence and Outcomes of Biliary Atresia
URI https://onlinelibrary.wiley.com/doi/abs/10.1097%2FMPG.0b013e318282a913
https://www.ncbi.nlm.nih.gov/pubmed/23263590
https://search.proquest.com/docview/1320164212
Volume 56
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