A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle - Crossland, Hannah; Constantin‐Teodosiu, Dumitru; Gardiner, Sheila M.; Constantin, Despina; Greenhaff, Paul L. (The Journal of physiology, 2008)
Keywords: Animals; Carbohydrate Metabolism; Forkhead Box Protein O3; Forkhead Transcription Factors - genetics; Forkhead Transcription Factors - metabolism; Insulin Resistance - genetics; Insulin Resistance - physiology; Integrative; Male; Models, Biological; Muscle Proteins - genetics; Muscle Proteins - metabolism; Muscle, Skeletal - metabolism; Muscular Atrophy - etiology; Muscular Atrophy - genetics; Muscular Atrophy - metabolism; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Oxidation-Reduction; Protein-Serine-Threonine Kinases - genetics; Protein-Serine-Threonine Kinases - metabolism; Proto-Oncogene Proteins c-akt - genetics; Proto-Oncogene Proteins c-akt - metabolism; Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase; Rats; Rats, Sprague-Dawley; RNA, Messenger - genetics; RNA, Messenger - metabolism; Sepsis - complications; Sepsis - genetics; Sepsis - metabolism; Signal Transduction; SKP Cullin F-Box Protein Ligases - genetics; SKP Cullin F-Box Protein Ligases - metabolism