Defining the Neural Mechanisms of Probabilistic Reversal Learning Using Event-Related Functional Magnetic Resonance Imaging

• Published in: The Journal of neuroscience Vol. 22; no. 11; pp. 4563 - 4567
• Main Authors: Cools, Roshan, Clark, Luke, Owen, Adrian M, Robbins, Trevor W
• Format: Journal Article
• Language: English
• Published: United States Soc Neuroscience 01.06.2002; Society for Neuroscience
• Subjects: Adult; Behavior; Brain - anatomy & histology; Brain - physiology; Brain Mapping; Corpus Striatum - physiology; Feedback, Psychological - physiology; Female; Humans; Magnetic Resonance Imaging; Male; Neural Inhibition - physiology; Neurons - physiology; Prefrontal Cortex - physiology; Probability Learning; Reversal Learning - physiology; Reward

Event-related functional magnetic resonance imaging was used to measure blood oxygenation level-dependent responses in 13 young healthy human volunteers during performance of a probabilistic reversal-learning task. The task allowed the separate investigation of the relearning of stimulus-reward asso...