Stability of Dengue 2 Nonstructural Glycoprotein 1 (NS1) Is Affected by the Nature of Basic Residue at Position NS1-324

• Published in: Current Issues in Molecular Biology Vol. 45; no. 2; pp. 1644 - 1654
• Main Authors: Ogire, Eva, El-Kalamouni, Chaker, Desprès, Philippe, Roche, Marjolaine
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 14.02.2023; MDPI
• Subjects: Communication; Dengue; dengue virus; Dengue viruses; Health aspects; Huh7 cells; Infection; Life Sciences; Lysine; lysine residue; Microbiology and Parasitology; non-structural protein 1; recombinant viral protein; Scientific equipment and supplies industry; ubiquitin-proteasome system; France; United States; Tanzania; Huh7 cells; ubiquitin-proteasome system; inflammation; lysine residue; dengue virus; non-structural protein 1; recombinant viral protein; oxidative stress; Oxidative stress; Non-structural protein 1; Recombinant viral protein; Inflammation; Dengue virus; Ubiquitin-proteasome system; Lysine residue

Dengue is the most prevalent mosquito-borne viral disease. It is caused by the infection of any of the four dengue virus (DENV) serotypes DENV-1 to DENV-4. The DENV non-structural glycoprotein 1 (NS1) plays an important role in virus replication and the immunopathogenesis of virus infection. The NS1...