Identifying cross-tissue molecular targets of lung function by multi-omics integration analysis from DNA methylation and gene expression of diverse human tissues - Peng, Shisheng; Fang, Jinlong; Mo, Weiliang; Hu, Guodong; Wu, Senquan (BMC genomics, 2025)
Keywords: Bayesian analysis; Biological analysis; Blood; Blood cells; CD46 antigen; Chronic obstructive pulmonary disease; Cross-tissue targets; Datasets; Deoxyribonucleic acid; DNA; DNA Methylation; Epigenetics; Gene expression; Gene Expression Profiling; Gene Expression Regulation; Gene loci; Gene mapping; Genes; Genetic analysis; Genetic aspects; Genetic research; Genome-wide association studies; Genome-Wide Association Study; Genomes; Human tissues; Humans; Lung - metabolism; Lung - physiology; Lung diseases; Lung function; Lungs; Methylation; Multi-omics analysis; Multiomics; Organ Specificity - genetics; Phenotypes; Physiological aspects; Protein expression; Proteins; Quantitative Trait Loci; Respiratory function; Tissues; China; DNA methylation; Lung function; Cross-tissue targets; Gene expression; Multi-omics analysis