The Infection Attack Rate and Severity of 2009 Pandemic H1N1 Influenza in Hong Kong

• Published in: Clinical infectious diseases Vol. 51; no. 10; pp. 1184 - 1191
• Main Authors: Wu, Joseph T., Ma, Edward S. K., Lee, Cheuk Kwong, Chu, Daniel K. W., Ho, Po-Lai, Shen, Angela L., Ho, Andrew, Hung, Ivan F. N., Riley, Steven, Ho, Lai Ming, Lin, Che Kit, Tsang, Thomas, Lo, Su-Vui, Lau, Yu-Lung, Leung, Gabriel M., Cowling, Benjamin J., Peiris, J. S. Malik
• Format: Journal Article
• Language: English
• Published: Oxford The University of Chicago Press 15.11.2010; University of Chicago Press; Oxford University Press
• Subjects: Adolescent; Adult; Antibodies; Antibodies, Viral - blood; ARTICLES AND COMMENTARIES; Biological and medical sciences; Child; Child, Preschool; Clinical medicine; Cross-Sectional Studies; Disease Outbreaks - statistics & numerical data; Disease transmission; Epidemiology; H1N1 subtype influenza A virus; Hong Kong - epidemiology; Hospital admissions; Human viral diseases; Humans; Immunoglobulin G - blood; Infections; Infectious diseases; Influenza A virus; Influenza A Virus, H1N1 Subtype - immunology; Influenza, Human - epidemiology; Influenza, Human - immunology; Influenza, Human - virology; Intensive care units; Markov Chains; Medical sciences; Middle Aged; Monte Carlo Method; Mortality; Neutralization Tests; Older adults; Pandemics; Reproducibility of Results; School age children; Seroepidemiologic Studies; Swine flu; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Hong Kong; Asia; China; China, People's Rep., Hong Kong; Infection; Respiratory disease; H1N1 influenza; Viral disease

Background. Serial cross-sectional data on antibody levels to the 2009 pandemic H1N1 influenza A virus from a population can be used to estimate the infection attack rates and immunity against future infection in the community. Methods. From April through December 2009, we obtained 12,217 serum spec...