Anti-caries effect of CPP-ACP in irradiated nasopharyngeal carcinoma patients

• Published in: Clinical oral investigations Vol. 19; no. 5; pp. 1005 - 1011
• Main Authors: Sim, Christina P. C., Wee, Joseph, Xu, Ying, Cheung, Yin-Bun, Soong, Yoke-Lim, Manton, David J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2015; Springer Nature B.V
• Subjects: Carcinoma - radiotherapy; Caseins - administration & dosage; Caseins - therapeutic use; Dental Caries - prevention & control; Dentistry; Disease Progression; Double-Blind Method; Female; Fluorides, Topical - administration & dosage; Fluorides, Topical - therapeutic use; Humans; Male; Medicine; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms - radiotherapy; Original Article; Treatment Outcome; Nasopharyngeal carcinoma; Dental caries; Remineralizing agent; Head and neck radiotherapy; CPP-ACP; Xerostomia

Objective The aim of this study was to determine the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on caries progression in irradiated nasopharyngeal carcinoma (NPC) patients. Methods Twenty-one males and three females (median age, 50 years) were randomized into two groups be...