Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

• Published in: Clinical microbiology and infection Vol. 28; no. 2; pp. 163 - 177
• Main Authors: Galmiche, Simon, Luong Nguyen, Liem Binh, Tartour, Eric, de Lamballerie, Xavier, Wittkop, Linda, Loubet, Paul, Launay, Odile
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2022; Elsevier for the European Society of Clinical Microbiology and Infectious Diseases; European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd
• Subjects: Aged; Antibodies, Viral; Cancer; COVID-19; COVID-19 Vaccines; Dialysis; Effectiveness; Efficacy; Humans; Immunocompromised Host; Immunogenicity; Life Sciences; Renal Dialysis; SARS-CoV-2; SARS-CoV-2 immunocompromised; Solid organ transplant; Systematic Review; Treatment Outcome; Vaccine; Vaccine Efficacy; COVID-19; SARS-CoV-2 immunocompromised; Effectiveness; Immunogenicity; Efficacy; Dialysis; Vaccine; Solid organ transplant; Cancer

Available data show that COVID-19 vaccines may be less effective in immunocompromised populations, who are at increased risk of severe COVID-19. We conducted a systematic review of literature to assess immunogenicity, efficacy and effectiveness of COVID-19 vaccines in immunocompromised populations....