Oxidative Stress Can Be Attenuated by 4-PBA Caused by High-Fat or Ammonia Nitrogen in Cultured Spotted Seabass: The Mechanism Is Related to Endoplasmic Reticulum Stress

• Published in: Antioxidants Vol. 11; no. 7; p. 1276
• Main Authors: Dong, Yanzou, Li, Lei, Xia, Tian, Wang, Lina, Xiao, Liping, Ding, Nengshui, Wu, Youlin, Lu, Kangle
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.06.2022; MDPI
• Subjects: 4-phenylbutyric acid; Ammonia; ammonia nitrogen exposure; Aquaculture; Aquatic animals; Diet; Dietary supplements; Endoplasmic reticulum; endoplasmic reticulum stress; Environmental factors; Experiments; Fish-culture; Gene expression; Health aspects; High fat diet; Lipid peroxidation; Liver; Methods; Nitrogen; Oxidative stress; Proteins; Statistical analysis; Ultrastructure; China; United States > US; ammonia nitrogen exposure; 4-phenylbutyric acid; endoplasmic reticulum stress; oxidative stress; high-fat diet

Oxidative stress is a common phenomenon in aquaculture, which can be induced by nutritional or environmental factors. Generally, oxidative stress causes poor growth performance, metabolic dysregulation, and even the death of aquatic animals. To identify a nutritional intervention strategy, high-fat...