Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

• Published in: Alzheimer's & dementia : translational research & clinical interventions Vol. 3; no. 3; pp. 440 - 449
• Main Authors: Lanctôt, Krista L., Amatniek, Joan, Ancoli-Israel, Sonia, Arnold, Steven E., Ballard, Clive, Cohen-Mansfield, Jiska, Ismail, Zahinoor, Lyketsos, Constantine, Miller, David S., Musiek, Erik, Osorio, Ricardo S., Rosenberg, Paul B., Satlin, Andrew, Steffens, David, Tariot, Pierre, Bain, Lisa J., Carrillo, Maria C., Hendrix, James A., Jurgens, Heidi, Boot, Brendon
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2017; John Wiley & Sons, Inc; Elsevier
• Subjects: Agitation; Alzheimer's disease; Anxiety; Apathy; Brain research; Caregivers; Clinical trials; Delusions; Dementia; Depression; Hallucinations; Hypothalamus; Institutionalization; Mental depression; Mortality; Neurobiology; Neuropsychiatric symptoms; Neurosciences; Older people; Psychosis; Psychotropic drugs; Review; Sleep; Sleep disturbance; Trial design; Apathy; Sleep disturbance; Agitation; Neuropsychiatric symptoms; Delusions; Trial design; Hallucinations; Depression; Alzheimer's disease

Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing substantial distress for both people with dementia and their caregivers, and contributing to early institutionalization. They are among the earliest signs and symptoms of neurocognitive disorders and incipient c...