The role of glutathione-S-transferase in anti-cancer drug resistance - Townsend, Danyelle M; Tew, Kenneth D (Oncogene, 2003)
Keywords: Antineoplastic Agents - metabolism; Antineoplastic Agents - pharmacology; Antitumor agents; Apoptosis; Asthma; Biological and medical sciences; c-Jun protein; Cancer; Cell Biology; Cell physiology; Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes; Cellular stress response; Chemotherapy; Detoxification; Drug development; Drug resistance; Drug Resistance, Neoplasm - drug effects; Enzyme inhibitors; Enzyme Inhibitors - metabolism; Enzyme Inhibitors - pharmacology; Enzyme Inhibitors - therapeutic use; Enzymes; Etiology; Fundamental and applied biological sciences. Psychology; Glutathione; Glutathione transferase; Glutathione Transferase - antagonists & inhibitors; Glutathione Transferase - metabolism; Human Genetics; Humans; Inactivation, Metabolic; Internal Medicine; Isoenzymes; JNK protein; Kinases; Leukotrienes; Ligands; MAP kinase; MAP Kinase Signaling System; Medicine; Medicine & Public Health; Molecular and cellular biology; Multiple sclerosis; Neoplasms - drug therapy; Neoplasms - enzymology; Neurodegenerative diseases; Oncology; Oxidative stress; Prostaglandins; Protein interaction; Proteins; review; Therapeutic targets; Transcription factors; Tumors; MAP kinase pathway; GST; polymorphism; resistance; Resistance; Enzyme; Glutathione transferase; Transferases; Mitogen-activated protein kinase; Malignant tumor; Carcinogenesis; Polymorphism