The putative tumor suppressor Zc3h12d modulates toll-like receptor signaling in macrophages - Huang, Shengping; Qi, Dongfei; Liang, Jian; Miao, Ruidong; Minagawa, Kentaro; Quinn, Tim; Matsui, Toshimitsu; Fan, Daping; Liu, Jianguo; Fu, Mingui (Cellular signalling, 2012)
Keywords: Animals; Cell Cycle Proteins; Endonucleases; Endoribonucleases; Extracellular Signal-Regulated MAP Kinases - genetics; Extracellular Signal-Regulated MAP Kinases - immunology; Extracellular Signal-Regulated MAP Kinases - metabolism; Feedback, Physiological; Gene Expression - immunology; HEK293 Cells; Humans; Immunity, Innate; inflammation; Inflammation - genetics; Inflammation - immunology; Inflammation - metabolism; JNK; lymph nodes; Macrophage; macrophage activation; Macrophage Activation - genetics; Macrophage Activation - immunology; macrophages; Macrophages - cytology; Macrophages - immunology; Macrophages - metabolism; Male; MAP Kinase Kinase 4 - genetics; MAP Kinase Kinase 4 - immunology; MAP Kinase Kinase 4 - metabolism; Mice; mitogen-activated protein kinase; NF-kappa B - genetics; NF-kappa B - immunology; NF-kappa B - metabolism; NF-κB; Proteins - genetics; Proteins - immunology; Proteins - metabolism; Signal transduction; Signal Transduction - immunology; spleen; Toll-like receptor; Toll-like receptor 2; Toll-Like Receptor 2 - genetics; Toll-Like Receptor 2 - immunology; Toll-Like Receptor 2 - metabolism; Toll-like receptor 4; Toll-Like Receptor 4 - genetics; Toll-Like Receptor 4 - immunology; Toll-Like Receptor 4 - metabolism; transcription factor NF-kappa B; tumor suppressor genes; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - immunology; Tumor Suppressor Proteins - metabolism; Ubiquitination; Signal transduction; NF-κB; JNK; Toll-like receptor; Macrophage