Chicken telomerase reverse transcriptase mediates LMH cell pyroptosis by regulating the nuclear factor-kappa B signaling pathway

• Published in: Poultry science Vol. 101; no. 6; p. 101826
• Main Authors: Xiang, Yong, Yu, Yun, Li, Qingbo, Chen, Jian, Li, Yu, Cao, Weisheng
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.06.2022; Elsevier
• Subjects: caspase-1; caspase-11; cell pyroptosis; chicken telomerase reverse transcriptase; chickens; genes; GENETICS AND MOLECULAR BIOLOGY; humans; interleukin-18; interleukin-6; LMH cells; NF-κB signaling pathway; phosphorylation; pyroptosis; telomerase; transcription factor NF-kappa B; chicken telomerase reverse transcriptase; LMH cells; cell pyroptosis; NF-κB signaling pathway

The activation of human telomerase reverse transcriptase is regulated by the nuclear factor kappa B (NF-κB) signaling pathway to various degrees to promote the occurrence and development of tumors. However, the regulatory roles of chicken telomerase reverse transcriptase (chTERT) and the NF-κB signa...