Branch point control at malonyl-CoA node: A computational framework to uncover the design principles of an ideal genetic-metabolic switch - Xu, Peng (Metabolic engineering communications, 2020)
Keywords: artificial intelligence; Autonomous oscillation; binding capacity; Biophysical models; Controller architecture; differential equation; enzymes; Escherichia coli; fatty acids; gene expression; malonyl coenzyme A; Metabolic engineering; Metabolic switches; protein degradation; repressor proteins; Special issue on The Natural Product Issue edited by Greg Stephanopoulos, Anthony Sinskey and Kang Zhou; Synthetic biology; transactivators; Metabolic switches; Metabolic engineering; Synthetic biology; Autonomous oscillation; Biophysical models; Controller architecture