Intersubunit Bridges of the Bacterial Ribosome

• Published in: Journal of molecular biology Vol. 428; no. 10; pp. 2146 - 2164
• Main Authors: Liu, Qi, Fredrick, Kurt
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 22.05.2016
• Subjects: Bacteria; Protein Biosynthesis - genetics; Protein Biosynthesis - physiology; protein synthesis; Ribosomes - genetics; Ribosomes - metabolism; Ribosomes - physiology; RNA, Messenger - genetics; RNA, Messenger - metabolism; RNA, Transfer - genetics; RNA, Transfer - metabolism; rRNA; translation; tRNA; CTD; tRNA; 30SIC; rRNA; translation; PoTC; protein synthesis; 70SIC; cryo-EM; PTC; NTD

The ribosome is a large two-subunit ribonucleoprotein machine that translates the genetic code in all cells, synthesizing proteins according to the sequence of the mRNA template. During translation, the primary substrates, transfer RNAs, pass through binding sites formed between the two subunits. Mu...