Effects of a mixture of mono-glycerides of butyric-, capric-, and caprylic acid with chlortetracycline on the growth performance, intestine morphology, and cecal microflora of broiler birds

• Published in: Poultry science Vol. 101; no. 2; p. 101617
• Main Authors: Lin, Qian, Liu, Yang, Li, Lily, Huai, Mingyan, Wang, Yanzhou, Lv, Tuo, Zhao, Haohan, Jiang, Guitao, Wang, Xin, Liu, Chunjie, Qiu, Huajiao, Dai, Qiuzhong
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.02.2022; Elsevier
• Subjects: Animal Feed - analysis; Animal Nutritional Physiological Phenomena; Animals; Bacteroides; blood serum; broiler; Caprylates; cecal microbiota; Chickens; chlortetracycline; Chlortetracycline - pharmacology; developmental stages; Diet - veterinary; dietary supplements; Dietary Supplements - analysis; Escherichia; Gastrointestinal Microbiome; Glycerides; growth performance; intestinal development; Intestines; Lactobacillus; Male; males; METABOLISM AND NUTRITION; microorganisms; mono-glyceride; octanoic acid; poultry industry; triacylglycerols; urea nitrogen; weight gain; mono-glyceride; growth performance; intestinal development; cecal microbiota; broiler
• ISSN: 0032-5791; 1525-3171; 1525-3171
• DOI: 10.1016/j.psj.2021.101617

This study aimed to investigate the effects of a mixture of mono-glycerides of butyric-, capric-, and caprylic acid (MMG) on the growth performance, intestinal morphology, and cecal microflora of broilers. A total of 960 male Arbor Acre broilers were offered basal diets with or without Chlortetracycline additive (CA) at 500 g/t, and MMG at 3,000, 1,000, or 650 g/t, with 8 replicates of 20 birds per treatment. The results confirmed 500 g/t CA with/without 1,000 g/t MMG increased the average daily weight gain (ADG) of birds compared to the control group 1 during the 42-d experimental period (P < 0.05). Comparing to the control group 1, 500 g/t CA with either 650 g or 1,000 g/t MMG or 1,000 g MMG alone increased the ADG of birds during the late growth stage (22–42 d) (P < 0.05). On d 42, the serum triglyceride levels were higher (P < 0.05) in groups supplemented with CA and CA + 1,000 g/t MMG comparing to the control group; while urea nitrogen level was higher in the control group comparing to the rest of treatment groups Compared to the control group 1, 1,000 g/t MMG alone without CA decreased the abundance of Faecalibacterium and Bacteroides but increased the abundance of Escherichia/Shiegella. About 500 g/t CA alone treatment group had higher abundance of Lactobacillus comparing to the rest of groups. In conclusion, dietary supplement with MMG showed beneficial efficacy on the growth and intestinal function of broilers, demonstrating the potential value of MMG to poultry industry. In terms of dosage, the current trial shows that 3,000 g/t (1–21 d) and 1,000 g/t (22–42 d) MMG without CA was the appropriate dietary supplemented rate for broilers. And the mixed use of 500 g/t CA and 1,000 g/t MMG was benefit for broilers at 22 to 42 d.