Enabling malic acid production from corn-stover hydrolysate in Lipomyces starkeyi via metabolic engineering and bioprocess optimization - Czajka, Jeffrey J.; Dai, Ziyu; Radivojević, Tijana; Kim, Joonhoon; Deng, Shuang; Lemmon, Teresa; Swita, Marie; Burnet, Meagan C; Munoz, Nathalie; Gao, Yuqian; Kim, Young-Mo; Hofstad, Beth; et al. (Microbial cell factories, 2025)
Keywords: Amino acids; Aspergillus oryzae - genetics; Bioreactors; Corn; Engineers; Fermentation; Genetic engineering; Genetically modified organisms; Hydrolysis; Lipids; Lipomyces - genetics; Lipomyces - metabolism; Lipomyces starkeyi; Machine learning; Machine learning medium optimization; Malate Dehydrogenase - genetics; Malate Dehydrogenase - metabolism; Malates - metabolism; Malic acid; Malic acid production; Metabolic engineering; Metabolic Engineering - methods; Methods; Oleaginous yeast; Physiological aspects; Pyruvate Carboxylase - genetics; Pyruvate Carboxylase - metabolism; Yeast fungi; Zea mays - chemistry; Zea mays - metabolism; United States; Malic acid production; Machine learning medium optimization; Oleaginous yeast; Lipomyces starkeyi